Mast Cell Activation Syndrome

Mast Cell Activation Syndrome is a complex immune system disorder characterized by the release of an inappropriate amount of inflammatory chemicals from mast cells in the body.

What is Mast Cell Activation Syndrome?

Mast Cell Activation Syndrome (MCAS) is a complex immune system disorder characterized by the release of an inappropriate amount of inflammatory chemicals from mast cells in the body. Mast cells are crucial players in the body’s immune response and are distributed throughout various tissues of the body, where they play a pivotal role in defending the body against threats including environmental triggers and pathogens. In MCAS, however, these cells become hypersensitive and overreact to seemingly harmless triggers, releasing excessive amounts of chemical mediators including histamine. This uncontrolled release can lead to a wide array of allergies and other inflammatory symptoms affecting multiple systems, including the skin, gastrointestinal tract, cardiovascular system, and respiratory system.

Symptoms can range from:

  • Extreme Allergic Reactions
  • Rapid Pulse
  • Low Blood Pressure
  • Fainting/Passing Out
  • Itchy Skin
  • Hives
  • Flushing/Redness of the Skin
  • Wheezing/Shortness of Breath
  • Diarrhea
  • Nausea and/or Vomiting
  • Cramps/Abdominal Pain 

The diagnosis of MCAS is challenging, often involving a meticulous evaluation of clinical history, symptom patterns, and laboratory tests. Although the precise cause(s) can be elusive, the evolving understanding of MCAS is opening doors for targeted treatments aimed at modulating mast cell activity, looking for factors that may trigger or exacerbate MCAS symptoms, and alleviating the diverse and often debilitating symptoms associated with this syndrome.

How can Well Integrative Medicine help me?

Well Integrative Medicine offers a holistic and patient-centered approach that can be particularly beneficial for individuals grappling with Mast Cell Activation Syndrome. Unlike traditional medical models, functional medicine not only treats the condition but also looks for the underlying factors contributing to mast cell dysfunction to address it.

Through in-depth assessments of genetic, environmental, and lifestyle factors, functional medicine practitioners tailor individualized treatment plans for patients with MCAS disorders. This approach may involve dietary modifications, addressing gut health, and identifying and minimizing exposure to potential triggers. By focusing on optimizing the body’s overall function and reducing inflammation, functional medicine seeks to provide comprehensive relief for MCAS patients. This integrative approach acknowledges the interconnectedness of various bodily systems, emphasizing the importance of personalized care to manage symptoms effectively and improve the overall quality of life for individuals navigating the complexities of Mast Cell Activation Syndrome.

Request a consultation at Well Integrative Medicine in Chicago

Embark on your journey to wellness with Well Integrative Medicine, your trusted partner in functional medicine in Chicago. If you’re grappling with Mast Cell Activation Syndrome (MCAS) or suspect you may be experiencing its challenges, don’t navigate this complex disorder alone. 

Our expert team is dedicated to providing personalized care that delves into the factors that can contribute to MCAS, offering comprehensive solutions tailored to your unique needs. Take the first step towards relief and a healthier life by requesting an appointment today. Call us at 773-784-7000 to begin your path to optimal well-being. Your care and comfort are our top priorities.


We're happy to answer any questions you may have, feel free to call us at
(773) 784-7000